Benzocaine UK Benzo Cristalline Anesthesin Bulk Cocaine Cutting Agent USA

Benzocaine UK Benzo Cristalline Anesthesin Bulk Cocaine Cutting Agent USA

Benzocaine
Chemical Name: 4-AMINOBENZOIC ACID ETHYL ESTER
Benzocaine CAS No : 94-09-7
Benzocaine Molecular Formula: C9H11NO2
Benzocaine Molecular Weight: 165.19
EINECS No: 202-303-5
Benzocaine Other names: anesthesin; Americaine; ETHYL 4-AMINOBENZOATE; ETHYL P-AMINOBENZOATE
Benzocaine Trade names: Anbesol, Cepacol, Lanacane
Benzocaine Appearance: White Crystalline Powder (Grain size: 20-60 Mesh and 200 Mesh)
Benzocaine Melting point:89.9-90.9 °C
Density: 1.17 g/cm3
Flash point:172°C/13mm
Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
Benzocaine Solubility: Soluble in ethanol, chloroform, ethyl ether and dilute acids. Sparingly soluble in water.

Benzocaine USP Pharm Materials Chemical Test Specification (COA) : 

benzocaine_COA
benzocaine_COA

Mechanism of Benzocaine action:
Pain is caused by the stimulation of free nerve endings. When the nerve endings are stimulated, sodium enters the neuron, causing depolarization of the nerve and subsequent initiation of an action potential. The action potential is propagated down the nerve toward the central nervous system, which interprets this as pain. Benzocaine acts to inhibit the voltage-dependent sodium channels (VDSCs) on the neuron membrane, stopping the propagation of the action potential.

Benzocaine Uses
Benzocaine is indicated to treat a variety of pain-related conditions. It may be used for:

Local anesthesia of oral and pharyngeal mucous membranes (sore throat, cold sores, mouth ulcers, toothache, sore gums, denture irritation)
Otic pain (earache)
Surgical or procedural local anesthesia
Formulations
Benzocaine can come in a variety of preparations including:
Oral preparations:

Lozenges (ex. Cepacol, Mycinettes)
Topical preparations:

Aerosol (ex. Topex)
Gel (ex. Orajel)
Paste (ex. Orabase)

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