Prilocaine USP Pharma Materials Prilocaine Hydrochloride Crystalline Prilocaine Hcl EP

Prilocaine USP Pharma Materials Prilocaine Hydrochloride Crystalline Prilocaine Hcl EP

Prilocaine USP Pharma Materials Prilocaine Hydrochloride Crystalline Prilocaine Hcl EP

Prilocaine Hcl
Name: Prilocaine Hydrochloride
CAS No:    1786-81-8
Molecular Formula: C13H21ClN2O
Molecular Weight: 256.77
EINECS No: 217-244-0
Appearance: White Solid
Melting point:    168-170°C
Use: Prilocaine is a local anesthetic of the amino amide type. In its injectable form (trade name Citanest), it is often used in dentistry. It is also often combined with lidocaine as a topical preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions like paresthesia. As it has low cardiac toxicity, it is commonly used for intravenous regional anaesthesia .

Prilocaine Hydrochloride USP Pharm Materials Chemical Test Specification (COA) : 

Product name
Prilocaine hydrochloride
CAS
CAS No.
1786-81-8
Outer Packing
25kg
25kg
Production date
2016.03.11
Shelf life
2018.03.10
Standard adopted
USP36
USP36
Items of analysis
Specification
Results
Description
White crystalline powder
Complies
Solubility
,,,
Freely soluble in water and in alcohol ,slightly soluble in chloroform,very slightly soluble in acetone; practically insoluble in ether
Complies
Identification
By IR absorption,To match with working standard
Complies
Identification
Should be positive response
Complies
Identification
Should display the reaction of chloride differentiated
Complies
Melting Point
166~169ºC
166~169ºC
166~168ºC
166~168ºC
Loss on drying
≤ 0.3%
≤ 0.3%
0.13%
0.13%
Residue on ignition
≤0.1%
≤0.1%
0.03%
0.03%
Heavy metals
≤0.002%
≤0.002%
<0.002%
<0.002%
Residual solvents
Should be to match with the standard
Complies
Assay
99.0% ~101.0%()
99.0% ~101.0%(on the anhydrous basis )
99.46%
99.46%
Conclusion
Qualified

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