Oxiracetam Nootropic Pharma Raw Materials Brain Improving Smart Chemicals

Oxiracetam Nootropic Pharma Raw Materials Brain Improving Smart Chemicals

Oxiracetam Nootropic Pharma Raw Materials Brain Improving Smart Chemicals

Product Name:   Oxiracetam
Synonyms:    4-HYDROXY-2-OXOPYRROLIDINE-N-ACETAMIDE;4-hydroxy-2-oxo-1-pyrrolidineacetamid;4-hydroxy-2-oxo-1-pyrrolidineacetamide;4-hydroxypiracetam;OXIRACETAM
CAS:    62613-82-5
MF:    C6H10N2O3
MW:    158.16
Chemical Properties    Whie Solid
Melting point:    165-168 °C
Density :    1.416

Oxiracetam Uses:  Nootropic. Analog of Piracetam with psychostimulant activity.
Indications and Usage    Oxiracetam, Piracetam and Aniracetam, are three commonly used brain metabolism-improving drugs and are pyrrolidone derivatives. They were developed in 1974 by the Italian company ICF and went on sale in 1987.
Oxiracetam is a Piracetam derivative and excites the central nervous system, promotes brain metabolism, significantly increases and promotes memory retention, and effectively treats senile memory and mental decline. It is used to treat brain dysfunction psychiatric syndrome and mental disorders. It can improve the memory and learning abilities of patients with senile dementia or memory disorders. It is suitable for treating neural dysfunction, memory disorder and intelligence disorders caused by brain damage. It can also be used as a recovery treatment for neurosis, brain trauma, encephalitis, and other brain diseases. Oxiracetam’s greatest advantage is that it is very soluble in water, making it suitable for injection. Research shows that Oxiracetam has higher pharmacological activity and significant curative effects compared to Piracetam.

Oxiracetam Mechanisms of Action    Oxiracetam’s mechanisms of action are similar to those of Piracetam. It promotes the binding of phosphorylcholine and phosphoethanolamine, increases the ratio of ATP/ADP in the brain, and increases the binding of protein with nucleic acids in the brain, thus improving the memory and learning ability of patients with senile dementia and memory disorder.
Pharmacokinetics    After intake, most of the drug will not accumulate in the body and will be excreted through urine in its original form. It is well-absorbed and well-tolerated.
Clinical Research    Animal trials showed that in all types of behavioral experiments, Oxiracetam can improve memory retention and learning ability, reduce brain shocks’ damage on memory, and prevent the learning abilities of rats suffering from spontaneous hypertensive cerebrovascular injury from decreasing. It can also increase acetylcholine circulation in rats’ skin and hippocampus, thus increasing affinity for choline uptake.

Oxiracetam Pharma Materials Chemical Tests (COA) :

Product name
Oxiracetam
CAS
CAS No.
62613-82-5
Outer Packing
25KG
25KG/drum
Production date
2017.03.20
Shelf life
2019.03.19
Standard adopted
Enterprise Standard.
Items of analysis
Specification
Results
Appearance
White crystalline powder
Conforms
Identification
Conforms
Conforms
Melting point
167ºC~170ºC
167ºC~170ºC
168.7ºC~169.6ºC
168.7ºC~169.6ºC
(470nm 1%)
Transmittance of 1% aqueous solution at 470nm
≥ 99%
NLT 99%
99.6%
99.6%
Ammonium ion
≤10 ppm
NMT 10 ppm
Conforms
Chlorides
≤50 ppm
NMT 50 ppm
Conforms
Residue on ignition
≤0.1%
NMT 0.1%
0.04%
0.04%
Heavy metals
≤10 ppm
NMT 10 ppm
Conforms
Loss on drying
≤1.0%
NMT 1.0%
0.37%
0.37%
Residual solvent
≤ 600 ppm
NMT 600 ppm
Conforms
Single impurity
≤0.1%
NMT 0.1%
0.04%
0.04%
Total impurities
≤0.1%
NMT 0.1 %
0.06%
0.06%
Assay
≥99.0%
NMT 99.0%
99.8 %
99.8 %
Conclusion
Qualified

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