Procaine hydrochloride Crystal Procaine Base Novocain Ethocaine Manufacturer
Product Name: Procaine Hcl, Novocain Hcl, Ethocaine Hcl.
CAS No: 51-05-8
Molecular Formula: C13H21ClN2O2
Molecular Weight: 272.77
EINECS No: 200-077-2
Appearance: white crystal or crystalline powder.
Melting point: 155-156 °C
Product Name: PROCAINE
Other Name: Novocain, Ethocaine
Molecular Formula: C13H20N2O2
Molecular Weight: 236.31
EINECS No: 200-426-9
Procaine hydrochloride Local anesthetic Info:
Procaine hydrochloride is a topical anesthetic, which can block the nerve fiber conduction
temporarilyand has a narcotic effect,strong effect, low toxicity, and non-addictive, but on
the skin, mucosal penetration is weak, unsuitable for surface anesthesia, patients are used
for infiltration, conduction and spinal anesthesia.
White fine needle crystal or crystalline powder at room temperature, no smell, taste
slightly bitter and Ma, soluble in water, soluble in ethanol, slightly soluble in
chloroform, almost insoluble in ether. Procaine hydrochloride ester bond structure can be
hydrolyzed to produce amino acid and diethylaminoethanol, under certain conditions, the
amino acid may be further decarboxylated toxic aniline.
The structure of procaine hydrochloride with aromatic primary amino, easy oxidation
discoloration pH, temperature, UV, oxygen and metal ions can accelerate the oxidation
discoloration. The aqueous solution was stable in pH3.0~5. So preparation of procaine
hydrochloride injection, it generally takes add acid to regulate pH 3.3 to 5.5, and
strictly control the sterilization temperature and time. to 100 ºC steam sterilization
30min circulation is appropriate, and should pay attention to shading, sealed save.
Procaine hydrochloride Uses Local anesthesic;Na+ channel blocker
Uses Procaine is a local anesthetic of the amino ester group that is primarily used as a
topical anesthetic. Procaine is also used to control the pain of intramuscular injection of
penicillin as well as in dentistry.