Rimonabant SR141716 Rimonabant hydrochloride Pharma Weight Loss Chemical ACOMPLIA

Rimonabant SR141716 Rimonabant hydrochloride Pharma Weight Loss Chemical ACOMPLIA

Rimonabant SR141716 Rimonabant hydrochloride Pharma Weight Loss Chemical ACOMPLIA

Rimonabant (SR141716)
Synonyms:    ACOMPLIA;RIMONABANT;RIMONABANT(ACOMPLIA,SR141716);5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-piperidinopyrazole-3-carboxamide;1H-Pyrazole-3-carboxamide, 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-;5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide
CAS:    168273-06-1
MF:    C22H21Cl3N4O
MW:    463.79

Rimonabant hydrochloride
MF:    C22H21Cl3N4O.ClH
MW:    500.25
CAS:    158681-13-1

Rimonabant (also known as SR141716; trade names Acomplia, Zimulti) was an anorectic antiobesity drug. Rimonabant is an inverse agonist for the cannabinoid receptor CB1 and was the first drug approved in that class. Rimonabant is a diet pills developed by the French company Sanofi-Aventis and the first cannabinoid type 1 receptor (CB1) antagonist for obesity treatment by selectively blocking marijuana in the EC system (Cannabinoid-1, CB1) receptors, can significantly reduce body weight, reduce waist circumference, reduce cardiovascular disease and other risk factors, but also can improve blood lipids and insulin resistance and metabolic syndrome, especially for There is a risk of clinical obesity or heart disease.

Rimonabant Pharma materials Chemical Test Specifications (COA):

Product Name
Product name
Rimonabant
Rimonabant
CAS
CAS No.
168273-06-1
Packing
Outer Packing
MFG
Production date
May 14th. 2015
EXPIRY DATE
Shelf life
May 13th. 2017
Products Standard
Standard adopted
Enterprise Standard
Analysis Item
Items of analysis
Quality Standard
Specification
Results
Results
Assay by (HPLC)
99%-101%
99.43%
Characters/appearance
White to off White powder
Complies
Odor and taste
Odorless
Complies
Identification
Positive reaction
Complies
Mesh size/sieve analysis
100% pass 80 mesh
Complies
Loss on drying
1% Max
0.78%
Water
≤2.0%
0.1%
Residue on ignition
01%Max
Complies
Single impurity
0.1% Max
Complies
Malting point
272.25 ºC
Complies
Bolling point
627 .69 ºC
Complies
Refractive Index
N20O1.67
Complies
PH
50-7.0
6.5
pK Values
pK. 11.31(Predicted). pK„ 3. 22 (Predicted)
Complies
Solubility
Soluble in ethanol (-20 mg/ml). DMSO (25 mg/ml) .DMF (-20mg/ml). and water (< 1 mg/ml)
Complies
Heavy Metals
NMT 10ppm
Complies
Microbiological Control
78cfu/g
78cfu/g
Total Plate Count
1000 cfu/g Max
Negative
Fungi
<100/g
Negative
Salmonella
Negative
Negative
Coll
negative
negative
Conclusion
Conclusion
Qualified

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